How do you take Beclomethasone; Neomycin; Chlorocresol?

Apply a thin layer of the cream (e.g. Polyderm Cream) to the affected area of skin 2 to 3 times daily. Gently rub it in and wash your hands after applying unless the hands are the area being treated. Do not use it for more than 7 to 14 days unless your doctor says so.

What are the side effects of Beclomethasone; Neomycin; Chlorocresol?

Mild burning or stinging when you first apply it, skin thinning if used for too long, itching or dryness at the application site, slight skin discolouration with prolonged use

Who should not take Beclomethasone; Neomycin; Chlorocresol?

People allergic to beclomethasone, neomycin, chlorocresol, or any aminoglycoside antibiotic should not use this cream. Do not use on viral skin infections like chickenpox or cold sores, fungal infections like ringworm, or on open wounds and broken skin. Avoid use on the face for prolonged periods.

Prescription

Topical corticosteroid with antibiotic

Beclomethasone; Neomycin; Chlorocresol

Q: What is Beclomethasone; Neomycin; Chlorocresol used for?

Skin rashes with infection, eczema with bacterial infection, itchy and inflamed skin, infected dermatitis, skin allergies with secondary infection

Last reviewed July 2026

Who is this for?

For adults (18+). Standard adult dosing applies: see the How to Take tab for full instructions.

What is this drug?

This is a combination cream that contains a steroid (beclomethasone) to reduce swelling and itching, an antibiotic (neomycin) to fight skin infections caused by bacteria, and a preservative (chlorocresol) to keep the cream safe for use. It works by calming inflamed skin while treating or preventing infection at the same time.

How it works

Binds to glucocorticoid receptors in the cytoplasm, translocating to the nucleus to suppress pro-inflammatory cytokine production and inhibit phospholipase A2, while neomycin inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, and chlorocresol provides additional antimicrobial activity through cell membrane disruption.

What is it used for?

Skin rashes with infectioneczema with bacterial infectionitchy and inflamed skininfected dermatitisskin allergies with secondary infection

Browse by condition

Bacterial Skin Infections Eczema & Skin Rashes

Prescription Required

You need a doctor's prescription to buy this drug.

Quick Interaction Check

Is Beclomethasone; safe to take with another drug?

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Similar drugs

Betamethasone; Fusidic acid

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What to watch out for

Always buy Polyderm Cream from a reputable pharmacy, avoiding roadside sellers as the cream may have been stored in hot conditions and could be expired or fake. Do not use this cream longer than your doctor prescribed, as overuse of steroid creams can permanently damage your skin. Do not share this cream with others even if they have similar skin problems, as they need to see a doctor for their own prescription.

Common Side Effects

Mild burning or stinging when you first apply it
skin thinning if used for too long
itching or dryness at the application site
slight skin discolouration with prolonged use

Serious Side Effects

Severe allergic reaction such as swelling of the face
rash spreading
or difficulty breathing requires immediate hospital care. If you notice stretch marks
unusual skin thinning
or the infection getting worse instead of better
stop using and see your doctor right away.

Drug Interactions

Avoid using other steroid creams or ointments on the same area at the same time as this can increase side effects. If you are taking any aminoglycoside antibiotics (like gentamicin injections), let your doctor know as neomycin belongs to the same family and combining them can increase the risk of side effects. Do not mix with other medicated creams unless your doctor approves.

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Pregnancy & Breastfeeding Warning

Do not use this cream during pregnancy or breastfeeding without consulting your doctor first, as the steroid component may be absorbed through the skin and could affect your baby.

Who Should NOT Take This

People allergic to beclomethasone
neomycin
chlorocresol
or any aminoglycoside antibiotic should not use this cream. Do not use on viral skin infections like chickenpox or cold sores
fungal infections like ringworm
or on open wounds and broken skin. Avoid use on the face for prolonged periods.

How to Store

Store in a cool, dry place below 25°C, avoiding direct sunlight or hot cars, as Nigerian heat can spoil the cream. Keep the tube tightly closed and out of the reach of children. Do not use it if the cream changes colour or smells different.

For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.