Antimalarial + Pain reliever (Analgesic/Antipyretic)
Last reviewed July 2026
Who is this for?
This is a combination medicine that contains two antimalarial drugs (artemether and lumefantrine) to kill the malaria parasite in your blood, plus paracetamol to bring down fever and relieve body pain while you recover.
Artemether inhibits malaria parasite protein synthesis by alkylating plasmodial proteins through endoperoxide bridge cleavage, while lumefantrine inhibits parasite heme polymerase and disrupts mitochondrial function; paracetamol inhibits COX enzymes in the central nervous system, reducing prostaglandin synthesis to alleviate fever and pain.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed one and continue your schedule. Do not take a double dose to make up. Try to complete all 6 doses within the 3 days for the medicine to work properly.
Complete the full 3-day course even if you feel better after the first day, as stopping early can make the malaria come back stronger. Buy only from licensed pharmacies, not roadside vendors, to avoid fake or expired drugs. Do not take additional paracetamol (Panadol, Boska, etc.) while using this medicine unless your doctor says so.
Avoid taking extra paracetamol (like Panadol or Emzor Paracetamol) while on this drug, as the combination already contains paracetamol and too much can damage your liver. Avoid alcohol, as it increases the risk of liver damage and can worsen dizziness. Tell your pharmacist if you are taking any heart medication, especially drugs for irregular heartbeat.
Check your specific combination
Is it safe to take Artemether; with your other drugs?
This medicine is generally not recommended in the first 3 months of pregnancy, so consult your doctor before using it if you are pregnant or breastfeeding.
Store in a cool, dry place away from direct sunlight and heat, avoiding hot cars or windows. Keep the medicine in its original pack and away from children. Nigeria's humidity can spoil medicines fast, so do not store in the bathroom.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.