Antihypertensive (Calcium Channel Blocker + ACE Inhibitor combination)
Brand of Amlodipine; Perindopril
Last reviewed June 2026
Who is this for?
This is a combination medicine containing two blood pressure-lowering drugs — Amlodipine (which relaxes your blood vessels) and Perindopril (which stops your body from producing a chemical that tightens blood vessels). Together, they work to bring your blood pressure down more effectively than either drug alone.
Blocks L-type calcium channels in vascular smooth muscle and cardiac tissue, causing vasodilation and reduced cardiac contractility, while inhibiting angiotensin-converting enzyme (ACE) to prevent angiotensin II formation, thereby reducing peripheral vascular resistance and blood pressure through complementary mechanisms.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Take one tablet once daily, preferably in the morning before food. Swallow it whole with a glass of water. Your doctor will decide which strength is right for you — common strengths in Nigeria include Coveram 5mg/5mg, 5mg/10mg, 10mg/5mg, and 10mg/10mg. Do not stop taking it even if you feel fine, as high blood pressure often has no symptoms.
If you miss a dose, skip it and take your next dose at the usual time the following morning. Do not take two tablets to make up for the missed one.
Only buy Coveram from licensed pharmacies — fake blood pressure medicines are common from roadside or unregistered sellers in Nigeria. Never stop this medicine suddenly because you feel better — high blood pressure is a silent killer and needs lifelong management. Check your blood pressure regularly at a pharmacy or clinic to make sure the medicine is working.
Avoid taking potassium supplements or salt substitutes that contain potassium, as Perindopril can raise potassium levels dangerously. NSAIDs like ibuprofen (e.g. Brufen) can reduce the blood pressure-lowering effect and harm your kidneys if used regularly. Alcohol can make dizziness and low blood pressure worse, so limit your intake.
Check your specific combination
Is it safe to take Amlodipine with your other drugs?
This drug is NOT safe during pregnancy — it can seriously harm or even kill your unborn baby, especially in the second and third trimesters. If you are pregnant, planning to become pregnant, or breastfeeding, tell your doctor immediately.
Store in a cool, dry place away from direct sunlight and heat — Nigeria's hot weather can damage medicines left in cars or near windows. Keep the tablets in their original pack and away from children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for Coveram 10 mg/10 mg Tablets
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NAFDAC Number
A4-6817
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