Skin protectant (barrier cream)
Last reviewed July 2026
Who is this for?
Zinc oxide is a mild skin protectant and barrier cream that works by forming a protective layer on the skin to keep out moisture, irritants, and germs, while also helping the skin heal.
Forms an occlusive physical barrier on the skin surface that blocks moisture loss, prevents contact irritants from penetrating the stratum corneum, and reflects ultraviolet radiation. This protective mechanism reduces transepidermal water loss and minimizes friction-induced inflammation while allowing normal skin respiration.
Available Over The Counter
Get this from any pharmacy or chemist: no prescription needed.
Explore this drug
Since zinc oxide cream is used as needed, there is no strict dosing schedule to miss. Simply apply it the next time you remember or the next time the skin needs protection.
Buy only from reputable pharmacies: avoid buying skin creams from roadside sellers or open markets where products may be expired or fake. This cream is for external use only: do not swallow it or apply it inside the eyes, nose, or mouth. If the skin condition does not improve after a few days, visit your doctor or pharmacist.
Zinc oxide cream is applied to the skin and does not usually interact with other medicines. However, avoid applying it at the same time as other medicated creams or ointments on the same spot: space them apart or ask your pharmacist. It does not interact with alcohol.
Check your specific combination
Is it safe to take Zinc with your other drugs?
Zinc oxide cream is generally considered safe for use during pregnancy and breastfeeding, as it stays on the skin surface and is not significantly absorbed into the body.
Store in a cool, dry place away from direct sunlight and heat: avoid leaving it in hot cars or near windows. Nigerian weather can be very hot, so keep it in a cupboard or drawer. Always keep it out of reach of children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.