Nasal Decongestant
Last reviewed July 2026
Who is this for?
Xylometazoline is a nasal decongestant that works by shrinking the swollen blood vessels inside your nose, making it easier for you to breathe when your nose is blocked.
Binds to alpha-2 adrenergic receptors on nasal blood vessels, causing vasoconstriction and reducing mucosal edema to relieve nasal congestion. This sympathomimetic action decreases blood flow to the nasal mucosa, allowing improved airway patency.
Available Over The Counter
Get this from any pharmacy or chemist: no prescription needed.
Explore this drug
Since you use this drug only when your nose is blocked, there is no strict schedule. If you forget a dose, just use it when you remember. Do not double the drops to make up for a missed one.
Do not use this drug for more than 7 days, as many Nigerians get used to nasal drops and keep using them for weeks or months, which actually makes the blocked nose worse. Buy trusted brands like Drutivin Nasal Drop or Xylo-Acino from a registered pharmacy, not from roadside sellers, because fake nasal drops can cause serious harm. Do not share your nasal spray or dropper bottle with anyone else to avoid spreading infections.
Do not use with MAO inhibitor drugs (some drugs used for depression) as this can cause a dangerous rise in blood pressure. Be careful if you are taking blood pressure medication, as xylometazoline can affect your blood pressure. Avoid using other nasal decongestant sprays or drops at the same time.
Check your specific combination
Is it safe to take Xylometazoline with your other drugs?
Do not use during pregnancy or breastfeeding unless your doctor specifically tells you it is safe, as it may affect blood flow and your baby.
Store at room temperature, away from direct sunlight and heat. Nigerian weather can be hot, so keep it in a cool, dry place, not inside a car or near a window. Keep the bottle tightly closed and out of children's reach. Throw it away 4 weeks after opening.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.