Antiviral
Last reviewed June 2026
Who is this for?
Valacyclovir is an antiviral medicine that works by stopping certain viruses from multiplying in your body — once you swallow it, your body converts it into acyclovir, which fights the virus directly.
Inhibits viral DNA polymerase by competing with deoxyguanosine triphosphate, preventing herpesvirus DNA replication and viral spread. The drug is metabolized to acyclovir, which requires phosphorylation by viral thymidine kinase to become active, ensuring selective targeting of infected cells.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
For cold sores: take 2 grams (four 500 mg tablets) twice a day for just 1 day. For genital herpes (first time): take one 1,000 mg dose (two 500 mg tablets) twice a day for 10 days. For shingles: take 1,000 mg three times a day for 7 days. Swallow with a full glass of water — you can take it with or without food. Start treatment as soon as you notice symptoms for best results.
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not take a double dose to make up for it.
Always buy from a licensed pharmacy — valacyclovir sold as Valtrex should have proper packaging, so avoid buying loose or unbranded tablets from roadside sellers. Drink plenty of water throughout the day while taking this medicine to protect your kidneys, especially in hot Nigerian weather. Do not share this medicine with anyone else, even if they have similar symptoms — it is a prescription drug meant specifically for you.
Be careful if you are taking other medicines that can affect your kidneys, such as some painkillers like ibuprofen or diclofenac taken regularly. If you are on any HIV medicines, tell your doctor as some may interact. Drinking plenty of water while on this medicine helps protect your kidneys.
Check your specific combination
Is it safe to take Valacyclovir with your other drugs?
Consult your doctor before taking valacyclovir if you are pregnant or breastfeeding — it should only be used if your doctor decides the benefit outweighs the risk.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep it in its original container and far away from children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
No brand names recorded for Valacyclovir yet.
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.