Keratolytic / Skin Moisturizer
Last reviewed June 2026
Who is this for?
Urea is a skin moisturizing and softening agent that works by drawing water into the outer layer of your skin and helping to remove dead, dry, or rough skin, making it smoother and softer.
Increases skin hydration by disrupting hydrogen bonds in the stratum corneum, promoting keratin dissolution and enhancing water penetration into the epidermis. Additionally, promotes desquamation of hyperkeratotic cells through proteolytic enzyme activation, facilitating removal of damaged keratin and revealing healthier underlying skin.
Available Over The Counter
Get this from any pharmacy or chemist — no prescription needed.
Explore this drug
Apply a thin layer of urea cream (like Jawa Urea Cream) to the affected area 1 to 3 times daily. Rub it in gently until absorbed. Wash your hands after applying unless you are treating your hands. It is for external skin use only — never swallow it or put it in your eyes.
If you forget to apply it, just put it on whenever you remember. Then continue with your normal routine. It is not dangerous to miss a dose since it is a skin cream, not a tablet you must take on schedule.
Buy your cream from a reputable pharmacy, not roadside sellers, to make sure it has not expired or been stored in the hot sun. Do not use urea cream as a bleaching product — it is meant for dry skin, not skin lightening. If your skin problem does not improve after a few weeks of use, see a doctor.
Avoid using other strong skin products like bleaching creams or harsh exfoliants on the same area at the same time, as this can cause serious irritation. If you are using any medicated cream prescribed by a doctor, ask your pharmacist before combining it with urea cream.
Check your specific combination
Is it safe to take Urea with your other drugs?
Urea cream applied on the skin is generally considered safe during pregnancy and breastfeeding, but it is wise to consult your doctor before using it, especially on large areas of the body.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can melt or spoil creams quickly. Keep the cap tightly closed after use. Always keep out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.