Edurant 25 mg Tablets Tablet (Rilpivirine) — Uses, Dosage & NAFDAC

Who is this for?

What is this drug?

Rilpivirine is an HIV medicine that works by blocking a protein the virus needs to make copies of itself, helping to reduce the amount of HIV in your blood and keep your immune system strong.

What is it used for?

HIV infection (used together with other HIV medicinesnot alone)

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HIV & AIDS

How it works

Inhibits HIV reverse transcriptase by binding non-competitively to the enzyme's allosteric site, preventing conversion of viral RNA to DNA and blocking HIV replication. Used in combination antiretroviral therapy to suppress viral load and prevent disease progression.

Prescription Required

You need a doctor's prescription to buy this drug.

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How to take this drug

Take one 25 mg tablet once a day, always with a full meal — not just a snack. Taking it without food means your body won't absorb the drug properly and it won't work well. Try to take it at the same time every day. In Nigeria, it is available as Edurant 25 mg Tablets.

What if I Miss a Dose?

If you remember within 12 hours of your usual time, take it right away with a meal. If more than 12 hours have passed, skip that dose and take the next one at your regular time. Never take two tablets to make up for a missed dose.

What to watch out for

Always take rilpivirine with a proper meal, not on an empty stomach — this is very important for the drug to work. Never stop taking your HIV medicines or skip doses even if you feel fine, as the virus can become resistant. Only buy from licensed pharmacies — do not purchase HIV medications from roadside vendors or unverified sources.

Common Side Effects

Trouble sleeping or strange dreams
headache
feeling dizzy
stomach upset or nausea
skin rash

Serious Side Effects

Severe skin rash with fever
blisters
or mouth sores — go to the hospital immediately. Signs of liver problems like yellowing of eyes or skin
dark urine
or constant stomach pain — see a doctor right away. Severe depression or unusual mood changes also need urgent medical attention.

Drug Interactions

Do not take rilpivirine with antacids or ulcer drugs like omeprazole (common in Nigeria for stomach problems) as they stop it from working — if you need an antacid, take it at least 2 hours before or 4 hours after rilpivirine. Rifampicin, used for treating TB, makes rilpivirine useless and must not be combined. Some herbal remedies and supplements, including St. John's Wort, can also reduce its effectiveness.

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Pregnancy & Breastfeeding Warning

If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before taking rilpivirine — your doctor will decide if it is safe for you and your baby.

Who Should NOT Take This

People allergic to rilpivirine or any ingredient in the tablet. People taking proton pump inhibitors like omeprazole or esomeprazole. People on rifampicin
carbamazepine
phenobarbital
phenytoin
or St. John's Wort. People with very high HIV viral loads may need a different medication — your doctor will advise.

How to Store

Store at room temperature, away from direct sunlight and heat. Keep the tablets in their original container with the lid tightly closed. Avoid storing in damp areas like the bathroom. Keep well out of reach of children.

For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.

Edurant 25 mg Tablets