Antimalarial
Last reviewed July 2026
Who is this for?
Quinine Sulfate is an antimalarial drug that works by killing the malaria parasites living inside your red blood cells, stopping them from multiplying and clearing the infection from your body.
Inhibits Plasmodium species growth by intercalating into parasitic DNA and RNA, disrupting nucleic acid synthesis and protein production within the malaria parasite. Additionally, increases intracellular calcium levels in skeletal muscle, reducing spontaneous muscle contractions and relieving nocturnal leg cramps.
Malaria (especially severe or stubborn malaria that has not responded to other antimalarials), muscle cramps (leg cramps at night)
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue as normal. Do not take two doses at once to make up for it.
Always buy your quinine from a licensed pharmacy. Brands like Alpaquine, Malacide, or Osyquine-300 are available in Nigeria, so avoid unbranded or roadside versions that may be fake or expired. Complete the full 7-day course even if you feel better after a few days, otherwise the malaria can come back stronger. If you notice ringing in your ears, blurred vision, or feel your heart racing, stop and see a doctor immediately.
Do not take quinine with mefloquine (another antimalarial) as it increases the risk of seizures and heart problems. Quinine can increase the effect of blood-thinning drugs like warfarin, causing dangerous bleeding. Avoid alcohol while taking quinine as it can worsen dizziness and stomach upset.
Check your specific combination
Is it safe to take Quinine with your other drugs?
Quinine can be used during pregnancy for severe malaria when the benefit outweighs the risk, but only under a doctor's strict supervision because it can cause low blood sugar in pregnant women and may affect the baby, so never self-medicate.
Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be hot, so avoid storing near windows or in cars. Keep the tablets in their original container and always keep out of reach of children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.