Combiworm Tablet Pyrantel Pamoate 125 mg

Who is this for?

Pyrantel (also called Pyrantel Pamoate) is a deworming medicine that works by paralyzing worms in your stomach and intestines so your body can flush them out naturally when you go to toilet.

Activates nicotinic acetylcholine receptors on nematode muscle cells, causing depolarization and sustained contraction that paralyzes the worm, allowing expulsion by normal intestinal peristalsis.

Is Pyrantel safe to take with another drug?

For adults, the usual dose is 11 mg per kg of body weight, taken as a single dose. For a 70 kg adult, this is roughly 3 tablets of the 250 mg strength or 6 tablets of the 125 mg strength (like Combiworm). You can take it with or without food — many people take it with a meal to reduce stomach upset. Chew the chewable tablet well before swallowing. For pinworm, your doctor may ask you to repeat the dose after 2 weeks.

Pyrantel is usually taken as a single one-time dose, so missing a dose is not common. If your doctor asked you to take a repeat dose after 2 weeks and you forget, take it as soon as you remember.

• Stomach cramps or mild belly pain
• feeling like vomiting (nausea)
• loose stool or diarrhea
• headache
• feeling dizzy or weak

Do not take Pyrantel together with Piperazine (another deworming medicine) — they cancel each other out and neither will work properly. If you are taking Theophylline for asthma, tell your doctor as Pyrantel may increase its levels in your blood. Alcohol is best avoided as it can worsen stomach upset and dizziness.

Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it on window sills or in cars. Keep the bottle or pack tightly closed to protect from humidity. Always keep out of reach of children.