Corticosteroid (anti-inflammatory steroid)
Last reviewed July 2026
Who is this for?
Prednisone is a steroid medicine that works by calming down your body's immune system and reducing swelling and inflammation, mimicking a natural hormone your body already produces.
Binds to cytoplasmic glucocorticoid receptors, translocating to the nucleus to suppress pro-inflammatory gene transcription and reduce production of cytokines, chemokines, and adhesion molecules. Additionally, inhibits phospholipase A2, decreasing arachidonic acid metabolism and prostaglandin/leukotriene synthesis, thereby suppressing immune cell activation and inflammatory responses across multiple tissues.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not take two doses at once to make up for it.
Never stop prednisone suddenly on your own, as stopping abruptly can cause serious withdrawal symptoms and even be life-threatening; your doctor must taper your dose gradually. Do not buy steroids from roadside vendors or use someone else's prescription. Long-term use requires regular check-ups, so keep all your doctor's appointments.
Avoid taking with NSAIDs like ibuprofen or diclofenac (Cataflam, Voltaren) as the combination increases the risk of stomach ulcers. If you are taking diabetes medicine, prednisone can raise your blood sugar and reduce its effectiveness. Alcohol should be avoided as it increases the risk of stomach problems.
Check your specific combination
Is it safe to take Prednisone with your other drugs?
Prednisone is not considered safe during pregnancy or breastfeeding unless your doctor decides the benefit outweighs the risk, so always consult your doctor before using it if you are pregnant, planning to become pregnant, or breastfeeding.
Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be very hot, so avoid leaving it in your car or near windows. Keep it in its original container with the lid tightly closed and far from children's reach.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.