Chi Gynocare Vaginal Ovules

Who is this for?

This is a combination medicine containing three active ingredients — Nystatin (an antifungal), Neomycin (an antibiotic), and Polymyxin B (another antibiotic) — that work together to fight fungal and bacterial infections in the vaginal area. It is available in Nigeria as Chi Gynocare Vaginal Ovules.

Nystatin binds to ergosterol in fungal cell membranes, disrupting membrane integrity and causing cell leakage; while Neomycin and Polymyxin B inhibit bacterial protein synthesis and disrupt bacterial cell wall/membrane integrity respectively, providing broad-spectrum coverage against gram-positive and gram-negative organisms.

Is Nystatin; safe to take with another drug?

Insert one vaginal ovule (pessary) deep into the vagina at bedtime, usually once daily for 14 days or as your doctor directs. Wash your hands before and after insertion. Lie down after inserting to prevent the ovule from slipping out. Complete the full course even if symptoms improve before the days are up.

If you forget to insert your ovule at bedtime, use it as soon as you remember. If it is almost time for the next dose, skip the missed one and continue your regular schedule. Do not use two ovules at once to make up for a missed dose.

• Mild burning or irritation in the vaginal area
• itching around the vagina after insertion
• slight increase in vaginal discharge

Avoid using other vaginal creams, pessaries, or douches at the same time unless your doctor says so. If you are using latex condoms or diaphragms, note that vaginal ovules may weaken them and reduce their effectiveness. Let your doctor know if you are taking any other antibiotics by mouth.

Store in a cool, dry place below 25°C — avoid leaving it in hot areas like inside a car or near a kitchen stove. Keep away from direct sunlight and moisture. Store out of the reach of children. In very hot weather, you can keep it in the refrigerator to maintain its shape.