Antibacterial and Antifungal combination
Brand of Metronidazole; Clotrimazole
Last reviewed June 2026
Who is this for?
This is a combination vaginal tablet containing two medicines — metronidazole (which fights bacteria and certain parasites) and clotrimazole (which fights fungal infections like yeast). Together, they treat mixed vaginal infections caused by both bacteria and fungi.
Inhibits bacterial DNA synthesis by intercalating into DNA and disrupting nucleic acid metabolism, while binding to fungal sterol 14α-demethylase to disrupt ergosterol synthesis and compromise fungal cell membrane integrity.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Insert one vaginal tablet deep into the vagina at bedtime, usually once daily for 7 to 10 days depending on your doctor's instruction. Wash your hands before and after insertion. Lie down after inserting to prevent the tablet from falling out. Do not swallow this tablet — it is meant only for the vagina.
If you forget to insert the tablet at bedtime, put it in as soon as you remember. If it is almost time for the next dose, skip the missed one and continue your normal schedule. Do not use two tablets at once to make up for a missed dose.
Complete the full course even if the discharge or itching stops early — stopping too soon can bring the infection back. Do not buy vaginal tablets from roadside vendors or open markets where storage conditions are poor. Avoid sexual intercourse during treatment, and your partner may also need to be treated to prevent the infection from coming back.
Avoid drinking alcohol while using this medication — metronidazole and alcohol together can cause serious nausea, vomiting, and stomach pain. If you are using blood thinners like warfarin, let your doctor know as metronidazole can increase their effect. Avoid using other vaginal creams or tablets at the same time unless your doctor says so.
Check your specific combination
Is it safe to take Metronidazole; with your other drugs?
Do not use this drug during pregnancy, especially in the first three months, or while breastfeeding unless your doctor specifically prescribes it for you.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep the tablets in their original pack until you are ready to use them. Keep away from children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for Regozole Vaginal Tablet
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NAFDAC Number
C4-1853
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