Immunomodulator (immune system regulator)
Last reviewed June 2026
Who is this for?
Interferon beta-1a is an injectable medicine made from a protein that your body naturally produces to regulate your immune system. It works by calming down the overactive immune system that mistakenly attacks the protective covering of your nerves.
Binds to interferon-beta receptors on immune cells, activating JAK-STAT signaling pathways that increase anti-inflammatory cytokine production and suppress pro-inflammatory T-cell responses. This reduces demyelinating inflammation in the central nervous system and decreases the frequency of disease relapses in multiple sclerosis.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
This is not a tablet — it is given as an injection under the skin (subcutaneous). The usual dose is 44 micrograms (one prefilled syringe of Rebif 44) injected three times a week, with at least 48 hours between each injection. Your doctor will start you on a lower dose and gradually increase it over the first few weeks. A nurse or doctor will teach you or a caregiver how to give the injection properly.
If you miss a dose, take it as soon as you remember, then continue your regular schedule. Do not take two doses within 48 hours of each other. Do not double up to make up for a missed dose — just skip it and carry on as normal.
This is a specialist prescription medicine — never buy it from roadside vendors or unregistered pharmacies, as it must be stored in cold conditions and fake versions can be dangerous. Always attend your regular doctor appointments and blood tests while on this medication so your liver and blood counts can be monitored. Do not share your injection with anyone else, even if they have similar symptoms.
Be careful if you are taking medicines that affect your liver, as interferon beta-1a can also stress the liver. Avoid excessive alcohol as it increases the risk of liver damage. If you are on epilepsy medicines or other drugs that lower your blood cell counts, inform your doctor before starting this injection.
Check your specific combination
Is it safe to take Interferon with your other drugs?
This medicine is not safe during pregnancy as it may cause miscarriage; use reliable contraception while on treatment and tell your doctor immediately if you become pregnant. Breastfeeding is not recommended without consulting your doctor.
Store Rebif 44 in a refrigerator (2°C to 8°C). In Nigeria's hot climate, never leave it outside the fridge or in direct sunlight — the heat will damage it. If you don't have a fridge, you can keep it at room temperature below 25°C for up to 28 days only, then throw it away. Keep it far away from children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.