Combination ear drop — Steroid, Antibiotics, and Local Anaesthetic
Last reviewed June 2026
Who is this for?
This is a combination ear drop that contains a steroid (fludrocortisone) to reduce swelling and inflammation, two antibiotics (neomycin and polymyxin B) to kill bacteria causing ear infections, and a numbing agent (lidocaine) to relieve ear pain quickly.
Inhibits bacterial protein synthesis via 30S ribosomal subunit binding (neomycin and polymyxin B), disrupts bacterial cell membrane integrity (polymyxin B), activates glucocorticoid receptors to suppress inflammatory cytokines and reduce edema (fludrocortisone), and blocks sodium channel influx to provide local anesthesia (lidocaine).
Prescription Required
You need a doctor's prescription to buy this drug.
Is Fludrocortisone; safe to take with another drug?
Check with multiple drugs →Explore this drug
For adults, put 2 to 5 drops into the affected ear 2 to 4 times daily as directed by your doctor. Tilt your head to the side and keep it tilted for about 5 minutes after putting in the drops so the medicine stays in. Do not use for more than 10 days unless your doctor says so.
If you miss a dose, put the drops in as soon as you remember. If it is almost time for the next dose, skip the missed one and continue your normal schedule. Do not double the drops to make up for a missed dose.
Important for antibiotics
Always complete the full course even if you feel better. Stopping early can cause the infection to return and become drug-resistant.
Buy only from a licensed pharmacy — Otomed Ear Drops sold by roadside vendors may be fake or expired. Complete the full course of treatment even if your ear feels better after a few days, otherwise the infection can come back. Do not share your ear drops with another person, as this can spread infection.
Avoid using other ear drops at the same time unless your doctor approves. If you are taking any aminoglycoside antibiotics (like gentamicin injections), tell your doctor as combining them with neomycin can increase the risk of hearing damage. There are no major food or alcohol interactions since this is applied in the ear.
Check your specific combination
Is it safe to take Fludrocortisone; with your other drugs?
If you are pregnant or breastfeeding, consult your doctor before using this ear drop — it should only be used if clearly needed and prescribed by a healthcare professional.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it on a window sill or in a hot car. Keep the bottle tightly closed and out of reach of children. Do not use after the expiry date on the pack.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.