Intelence 100 mg Tablet Tablet (Etravirine) — Uses, Dosage & NAFDAC

Who is this for?

What is this drug?

Etravirine is an antiretroviral (anti-HIV) medicine that works by blocking an enzyme called reverse transcriptase, which the HIV virus needs to multiply in your body, helping to reduce the amount of virus in your blood.

What is it used for?

HIV infection (used together with other HIV medicinesnot alone)

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HIV & AIDS

How it works

Inhibits HIV reverse transcriptase by binding to a hydrophobic pocket distinct from the nucleotide binding site, preventing viral RNA-dependent DNA synthesis and suppressing HIV replication. This mechanism allows activity against some reverse transcriptase mutants resistant to other NNRTIs.

Prescription Required

You need a doctor's prescription to buy this drug.

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How to take this drug

Take one 200 mg dose (two 100 mg tablets) twice daily, always after a meal — food helps your body absorb the drug properly. Swallow the tablets whole with water. If you have trouble swallowing, you can dissolve them in a glass of water and drink immediately. In Nigeria, you may find it as Intelence 100 mg Tablet.

What if I Miss a Dose?

If you miss a dose and it has been less than 6 hours since you were supposed to take it, take it right away with food. If more than 6 hours have passed, skip it and take your next dose at the regular time. Never take a double dose to make up for the missed one.

What to watch out for

Always get your HIV medicines from a licensed pharmacy or your treatment centre — never buy from roadside sellers or unverified sources, as fake drugs are dangerous. Do not stop taking this medicine or skip doses even if you feel fine, as the virus can become resistant and harder to treat. Do not share your HIV medicines with anyone else, even if they also have HIV.

Common Side Effects

Skin rash
nausea or stomach upset
diarrhea
headache
tiredness

Serious Side Effects

Severe skin rash with blisters
peeling
or sores in the mouth — stop the drug and go to the hospital immediately. Signs of liver problems like yellowing of the eyes or skin
dark urine
or severe stomach pain also need urgent medical attention. Severe allergic reactions with swelling of the face
difficulty breathing
or fever with body rash require emergency care.

Drug Interactions

Do not take etravirine with rifampicin (commonly used for TB treatment in Nigeria) as it makes etravirine much less effective. Avoid taking it with St. John's Wort herbal supplements. Tell your doctor if you are taking any other HIV medicines, seizure medicines, or blood thinners, as doses may need adjustment.

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Pregnancy & Breastfeeding Warning

Etravirine is not generally recommended during pregnancy or breastfeeding unless your doctor specifically decides the benefit outweighs the risk — always consult your doctor before using it if you are pregnant, planning to become pregnant, or breastfeeding.

Who Should NOT Take This

People who are allergic to etravirine or any of its ingredients should not take it. It should not be used alone — it must always be combined with other HIV medicines. People with severe liver disease should avoid this drug unless closely monitored by a doctor.

How to Store

Store at room temperature, away from direct sunlight, heat, and moisture — avoid storing in the bathroom or near a kitchen window. Keep the tablets in their original container with the cap tightly closed, and always keep out of the reach of children.

For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.

Intelence 100 mg Tablet