Hormone (Estrogen replacement)
Last reviewed July 2026
Who is this for?
Estradiol valerate is a form of the female hormone estrogen, made in the lab to work like the natural hormone your body produces. It replaces estrogen when your body is not making enough, helping to relieve symptoms caused by low estrogen levels.
Binds to estrogen receptors (ERα and ERβ) in target tissues, activating nuclear transcription of estrogen-responsive genes to restore hormonal homeostasis and alleviate menopausal symptoms while promoting bone mineral density and vaginal epithelial integrity.
Menopause symptoms (hot flashes, night sweats, vaginal dryness), hormone replacement after the ovaries are removed, prevention of weak bones (osteoporosis) in women after menopause
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed one. Do not take two tablets at once to make up for it.
Only buy from licensed pharmacies, avoiding roadside sellers or unverified online stores, as fake hormone drugs are common. Do not share this medication with anyone, even if they have similar symptoms. Attend your regular check-ups with your doctor while on this drug, as long-term use needs monitoring.
Some anti-seizure drugs like carbamazepine and phenytoin can reduce how well estradiol works. Herbal remedies like St. John's Wort can also reduce its effectiveness. Alcohol can increase the risk of side effects like dizziness and may worsen liver problems.
Check your specific combination
Is it safe to take Estradiol with your other drugs?
Estradiol valerate is NOT safe during pregnancy or breastfeeding. Stop taking it immediately if you find out you are pregnant and see your doctor.
Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be very hot, so avoid leaving it in cars or near windows. Keep it in its original pack and far from children's reach.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.