Anti-glaucoma combination (Beta-blocker + Carbonic anhydrase inhibitor)
Last reviewed July 2026
Who is this for?
This is a combination eye drop containing two medicines, dorzolamide and timolol, that work together to reduce pressure inside the eye by decreasing the amount of fluid the eye produces.
Inhibits carbonic anhydrase II in the ciliary body, reducing aqueous humour production, while simultaneously blocking beta-1 and beta-2 adrenergic receptors to decrease aqueous humour secretion and increase uveoscleral outflow, thereby lowering intraocular pressure.
High eye pressure (glaucoma), raised pressure inside the eye (ocular hypertension)
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you forget a dose, put the drop in as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not put in two drops at once to make up for it.
Always buy from a licensed pharmacy. Do not purchase from roadside sellers or unregistered shops, as fake eye drops can damage your eyes. Do not share your eye drops with anyone else, even if they have similar eye problems. If you wear contact lenses, remove them before putting in the drops and wait at least 15 minutes before putting them back in.
If you are using other eye drops, wait at least 10 minutes between each one. Oral beta-blockers (like atenolol or propranolol used for high blood pressure) can increase side effects when combined with this eye drop, so tell your doctor about all medicines you take. Avoid using with other carbonic anhydrase inhibitors like acetazolamide tablets as this increases the risk of side effects.
Check your specific combination
Is it safe to take Dorzolamide with your other drugs?
This medicine is not recommended during pregnancy or breastfeeding unless your doctor specifically prescribes it. Always consult your doctor first.
Store at room temperature away from direct sunlight and heat. Nigerian weather can be very hot, so keep it in a cool, dry place. Once opened, use within 28 days and throw away any remaining drops. Always keep out of reach of children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.