Antihistamine and Vitamin Supplement (Appetite Stimulant)
Last reviewed July 2026
Who is this for?
This is a combination drug that contains cyproheptadine (an antihistamine that also boosts appetite) along with B-vitamins (B1, B2, B6, and B12) that help your body use food better and stay healthy. It works by blocking certain chemicals in your body that reduce hunger, while the vitamins support your energy and overall nutrition.
Blocks H1 histamine receptors and serotonin receptors, stimulating appetite through central nervous system mechanisms, while B vitamins (B1, B2, B6, B12) function as essential coenzymes in carbohydrate metabolism, energy production, and red blood cell formation, thereby improving nutritional status and reducing fatigue associated with deficiency states.
Available Over The Counter
Get this from any pharmacy or chemist: no prescription needed.
Explore this drug
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, just skip the missed one and continue as normal. Do not take a double dose to make up for it.
This drug can make you very sleepy, so do not drive or operate machines after taking it. Buy only from licensed pharmacies, as products like Avro Apetit Syrup from roadside sellers may be fake or expired. Do not use this drug for longer than your doctor recommends just to gain weight, as long-term misuse can cause health problems.
Avoid drinking alcohol while taking this drug as it can make you very drowsy and dizzy. Be careful if you are taking sleeping pills, sedatives, or other antihistamines like chlorpheniramine or promethazine as the drowsiness can become dangerous. Also inform your doctor if you are taking antidepressants.
Check your specific combination
Is it safe to take Cyproheptadine with your other drugs?
This drug is not recommended during pregnancy or breastfeeding, so consult your doctor before using it if you are pregnant, planning to become pregnant, or nursing a baby.
Store in a cool, dry place away from direct sunlight and heat, as Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep the bottle tightly closed and always keep it out of the reach of children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.