Topical antibiotic and retinoid combination (anti-acne)
Last reviewed July 2026
Who is this for?
This is a combination gel containing two active ingredients: clindamycin (an antibiotic that kills bacteria on the skin) and adapalene (a vitamin A-based ingredient that unclogs pores and reduces swelling). Together, they fight acne from multiple angles.
Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, while adapalene activates retinoic acid receptors (RAR-γ and RAR-β) to normalize keratinocyte differentiation, reduce sebum production, and decrease comedone formation.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you forget to apply it at night, skip that dose and apply it the next night as usual. Do not apply extra the next time to make up for the missed dose.
Important for antibiotics
Always complete the full course even if you feel better. Stopping early can cause the infection to return and become drug-resistant.
Buy only from a reputable pharmacy: products like Norbacare Gel should be properly sealed and not expired. Your skin may look worse in the first 2-4 weeks before it gets better, so be patient and do not stop too early. Always use sunscreen during the day because adapalene makes your skin extra sensitive to sunlight, which is important in Nigeria's strong sun.
Avoid using other acne products containing benzoyl peroxide, salicylic acid, or strong exfoliants at the same time unless your doctor says so, as it can cause severe irritation. Do not use medicated soaps or harsh skin products alongside this gel. If you are taking erythromycin (another antibiotic), let your doctor know as it may reduce clindamycin's effectiveness.
Check your specific combination
Is it safe to take Clindamycin; with your other drugs?
Do not use this gel if you are pregnant or planning to become pregnant, as adapalene can harm the unborn baby; breastfeeding mothers should also consult a doctor before use.
Store in a cool, dry place away from direct sunlight and heat, as Nigerian weather can be very hot, so avoid leaving it in a car or near a window. Keep the tube tightly closed and out of reach of children. Do not refrigerate unless the label says so.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.