Advantec Tablets 16 mg + 12.5 mg

Who is this for?

This is a combination medicine containing two active ingredients — candesartan (which relaxes blood vessels) and hydrochlorothiazide (a 'water tablet' that helps your body get rid of extra salt and water). Together, they work to lower high blood pressure more effectively than either one alone.

Blocks angiotensin II type 1 (AT1) receptors, preventing vasoconstriction and aldosterone release, while hydrochlorothiazide inhibits sodium reabsorption in the distal convoluted tubule, promoting natriuresis and reducing blood volume to synergistically lower blood pressure.

Is Candesartan safe to take with another drug?

Usually one tablet taken once daily, with or without food. Swallow the tablet whole with a glass of water. Your doctor will decide the right strength for you — common combinations available in Nigeria include Atacand Plus (16/12.5 mg), Advantec (16/12.5 mg), and Candesartan/HCT Sandoz (8/12.5 mg). Try to take it at the same time every day so you don't forget.

If you miss a dose, take it as soon as you remember. But if it's almost time for your next dose, skip the missed one and continue as normal. Never take two tablets at once to make up for a missed dose.

• Dizziness or lightheadedness (especially when you stand up quickly)
• headache
• feeling tired or weak
• passing urine more often than usual
• mild stomach upset

Avoid taking this medicine with potassium supplements or potassium-rich salt substitutes, as it can cause dangerous changes in your potassium levels. NSAIDs like ibuprofen (commonly sold as Ibalgin or Brufen in Nigeria) can reduce the blood pressure-lowering effect and harm your kidneys. Drinking alcohol can increase dizziness and make your blood pressure drop too low.

Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep the tablets in their original pack and always store out of reach of children.