How do you take Brinzolamide?

Put one drop in the affected eye(s) two to three times a day, as your doctor directs. Shake the bottle well before use. After putting in the drop, gently press the corner of your eye near your nose for about 1-2 minutes to stop the medicine from draining away. Wait at least 5 minutes before using any other eye drops.

What are the side effects of Brinzolamide?

Temporary blurred vision after putting in the drop, bitter or unusual taste in your mouth, feeling like something is in your eye, mild eye irritation or redness, dry eyes

Who should not take Brinzolamide?

People allergic to brinzolamide or sulfonamide (sulfa) drugs should not use this medicine. People with severe kidney problems should avoid it. Do not use if you have a condition called hyperchloraemic acidosis. Always tell your doctor if you have any allergies before starting this drug.

Prescription

Carbonic anhydrase inhibitor (eye pressure-lowering medicine)

Brinzolamide

Last reviewed July 2026

Who is this for?

For adults (18+). Standard adult dosing applies: see the How to Take tab for full instructions.

What is this drug?

Brinzolamide is an eye drop medicine that lowers pressure inside the eye by reducing the amount of fluid the eye produces.

How it works

Inhibits carbonic anhydrase II enzyme in the ciliary body epithelium, reducing aqueous humour production and subsequently decreasing intraocular pressure in glaucoma and ocular hypertension.

What is it used for?

High eye pressure (ocular hypertension), glaucoma (a condition where high pressure in the eye can damage your sight over time)

Browse by condition

Glaucoma & Eye Pressure

Prescription Required

You need a doctor's prescription to buy this drug.

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What to watch out for

Only buy Azopt Eye Drops or brinzolamide from reputable pharmacies and avoid roadside or unregistered sellers, as fake eye drops can damage your eyes permanently. Do not share your eye drops with another person, even if they have similar symptoms. If your vision becomes blurred after using the drops, wait until it clears before driving or operating machinery.

Common Side Effects

Temporary blurred vision after putting in the drop
bitter or unusual taste in your mouth
feeling like something is in your eye
mild eye irritation or redness
dry eyes

Serious Side Effects

Severe eye pain
swelling
or discharge require immediate medical attention. Signs of allergic reaction such as swelling of the face
difficulty breathing
or severe skin rash mean you should go to the hospital right away. Persistent blurred vision or worsening eye symptoms need urgent medical attention.

Drug Interactions

If you are taking other eye drops, wait at least 5 minutes between each one to avoid washing out the medicine. Oral carbonic anhydrase inhibitors like acetazolamide (Diamox) should not be used together with brinzolamide as they work in a similar way and can increase side effects. Let your doctor know about all other medicines you are using.

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Pregnancy & Breastfeeding Warning

Brinzolamide is not recommended during pregnancy or breastfeeding unless your doctor says the benefit outweighs the risk, so always consult your doctor first.

Who Should NOT Take This

People allergic to brinzolamide or sulfonamide (sulfa) drugs should not use this medicine. People with severe kidney problems should avoid it. Do not use if you have a condition called hyperchloraemic acidosis. Always tell your doctor if you have any allergies before starting this drug.

How to Store

Store at room temperature, away from direct sunlight and heat. Do not freeze. Keep the bottle tightly closed when not in use. In Nigeria's hot climate, try to store it in a cool, dry place. Keep away from children. Discard the bottle 4 weeks after first opening it.

For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.