Antihypertensive (combination of calcium channel blocker, angiotensin receptor blocker, and thiazide diuretic)
Brand of Amlodipine; Valsartan; Hydrochlorothiazide
Last reviewed June 2026
Who is this for?
This is a combination tablet containing three blood pressure medicines — Amlodipine (which relaxes blood vessels), Valsartan (which blocks a chemical that tightens blood vessels), and Hydrochlorothiazide (a 'water tablet' that helps your body get rid of excess salt and water) — all working together to lower high blood pressure.
Blocks L-type calcium channels (amlodipine) to reduce vascular smooth muscle contraction, antagonizes angiotensin II type 1 receptors (valsartan) to inhibit vasoconstriction and aldosterone release, and inhibits sodium reabsorption in the distal convoluted tubule (hydrochlorothiazide) to promote natriuresis and reduce blood volume, collectively lowering systemic vascular resistance and blood pressure.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Take one tablet once daily, with or without food. Swallow the tablet whole with a full glass of water. Try to take it at the same time every day so you don't forget. Your doctor will choose the right strength based on how well your blood pressure is controlled.
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue as normal. Do not take two tablets at once to make up for a missed dose.
Only buy this medicine from licensed pharmacies — avoid roadside vendors or open market sellers, as fake blood pressure drugs are common in Nigeria. Do not stop taking this medicine suddenly because your blood pressure feels 'normal' — high blood pressure usually has no symptoms but still damages your body. Always check your blood pressure regularly at a pharmacy or clinic to make sure the medicine is working.
Avoid taking potassium supplements or potassium-containing salt substitutes without your doctor's approval, as Valsartan can raise potassium levels. Be careful with painkillers like ibuprofen or diclofenac (very common in Nigeria) as they can reduce the effectiveness of this medicine and harm your kidneys. Limit alcohol intake as it can increase dizziness and further lower your blood pressure.
Check your specific combination
Is it safe to take Amlodipine with your other drugs?
This medicine is NOT safe during pregnancy — it can seriously harm or even kill your unborn baby, especially in the second and third trimesters; also avoid it while breastfeeding, and tell your doctor immediately if you become pregnant.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near windows. Keep the tablets in their original pack and far away from children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for Amlodipine 5 mg, Valsartan 160 mg, Hydrochlorothiazide 12.5 mg
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NAFDAC Number
A4-100740
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